I don't care about socks, but my strong feelings on silverware hurt my family's brains en mass.
They have to be organized just right. If they aren't organized the way I like them it kills me. And I know when they're off. Once, I walked into the kitchen during a party and could not drag my eyes from the silverware drawer. After about five minutes I finally opened it to find that someone had put a knife in the wrong way round. A few weeks ago I spent a week on edge before I found that someone had put our smallest, wimpiest fork(which has its own spot, thank you) had been placed with the good forks. It's like I have a psychic link with the cutlery.
My family enjoys screwing with me over it. Of course, given the number of instructional rants I go on about it...
Love it! I am pretty laissez-faire about a lot of things now, less so when I was younger. I love the Miss Matched non-matching socks and my silverware and dishes are all random because I got most of them as hand-me-downs.
I do keep my cereal boxes in the fridge, though. This freaks people out sometimes. I started doing it years ago because I literally did not have any other place to store an open cereal box in my tiny kitchen. Now I find it convenient because they're right next to the milk, and the cereal is
cold. I don't like room-temperature cereal anymore. This leads to brain-hurting exchanges like, "No, we can't detour, we have to go straight home from the grocery store so I can put my cereal in the fridge!" Oh wait...
My friend and her family make my brain hurt with their domestic preferences. My friend was complaining once about her DH doing the laundry wrong--he'd put the towels in the washer, but he wasn't going to put the hand towels in then because he said they hadn't been used. She agreed they hadn't been used, but pointed out that if he washed the (matching) bath towels and hand towels a different number of times, eventually the color of the more-washed ones would fade, and then the two groups wouldn't match anymore. She explained this to a group of us like it was the most natural thing in the world, and we all just stared at her, because none of the rest of us had ever considered such a thing. Frankly I was thinking how awesome it was that her DH had, voluntarily, done everything else about the laundry correctly, and she had to nitpick on this one thing.
But then I went to visit her parents, and they're the same way. They have two different colors of dishes--think Fiestaware in dark and light--and they stack them in alternating colors in the cabinet, so they can easily lay them out in alternating colors on the table. And when dirty they put them in alternating colors in the dishwasher. At one meal they handed me a plate of one color, realized where I planned to sit, and took the plate away and gave me one of the other color. I was like

.
They are all really nice people, though, they just have their funny quirks as do we all.

My dad is really persnickety about how dishes go in the dishwasher, he'll come along after my mom has loaded it and rearrange things before running it.