I have a pearl ring that was bequeathed to my by my late grandmother when I was 8 yrs old. By the time I reached my 20's I decided to wear the ring daily. It was set in prongs, much like a diamond setting. I took it to a jeweler once because, after about 5 years of daily wear, the pearl started rolling in the setting. I thought the prongs came loose. Jeweler admonished me "You're wearing this every day, aren't you?" Sure enough the pearl was disintegrating.
My MIL gave me a pearl pendant of hers after LDH passed away. I wore it on a gold chain, never removed it, and it discolored, changed it's shape, and finally fell off of the pendant. I did not take proper care of that pearl.
On the flip side, my mother's engagement ring was a pearl. She only wears it for special occasions, or when going out to church or even shopping, pretty much whenever she left the house. She never wore it around the house. To this day it's as beautiful as it was 56 years ago.
Yes. Pearls are delicate. They can last a long time, if you don't abuse them.
OP -- that ring is gorgeous! If it makes you happy? I say go for it.