Oh, I have so many that I would need 10-20 posts just to name them all. I'll keep to local (NEPA) mispronunciations.
axe - ask
dahg - dog (sounds like a Boston accent with a more nasal tone)
chimbley - chimney (although chi-min-ee is running a close second)
dis, dat, dem, dese, dose, dere - this, that, them, these, those, there (PLEASE people! There is a "th" in there)
gooms - gums (as in the things that hold your teeth in your mouth)
Doverman Pincher - Doberman Pinscher
drownded - drowned
torTILLa - tortilla
kwehsahDILLa - quesadilla
fillum - film
tanks - thanks
Sayerday - Saturday
Eyetalian - Italian
skettie or pahsketti - spaghetti (I don't mind when small children do this; but grown ups?
A personal pet peeve is when people pronounce the abbreviation for avenue (Ave.). It just irritates the ehell out of me!