I don't think the asker truly thinks the OP's family needs a girl, I bet they think they are just being friendly and funny. But the coworker is also being dense. I'm childfree by choice and I have a close, longtime friend who kept telling me "You'll change your mind one day", "You'd make a great mom!" and stuff like that. I finally sent her an email and said "I know that when you say things like that, you're trying to be positive and encouraging and I'm flattered. But I don't think you realize how frustrating it is to keep hearing these things because I've been very clear about my choice to have children. I know you love me, so i can't understand why you won't accept my choice and keep insisting I do something that I strongly know I don't want to do. Also, while I'm childfree by choice, we have 2 mutual friends who are struggling with infertility and comments like this hurt them deeply because they are TRYING but can't have a baby. So while you mean well when you keep throwing out comments about us having kids, I need to you see that you are also doing harm by saying these things unsolicited. I've said I don't want kids, but you ignore that. They say nothing because the topic is painful but you keep bringing it up. So as a friend, I'm advising you to not comment on ANYONE's reproductive situation unless prompted to by the other person. Because repeatedly telling someone what they should do with their uterus without knowing their situation, or ignoring their words and thinking you know better, is just really really wrong."