At my elementary school, we were the deaf magnet school. I ended up in 6th grade being an aide to a younger student. I think he wasn't too many years younger than me, but he was blind, deaf, and had profound mental issues. But I went every week to go see him and do some basic activities with him, and he was always so happy to have me there.
We also had several deaf mainstream students, all they needed was an interpreter, and there was one for each grade, as well as a few extra on hand to switch out during the day.
When I got to high school, we had a girl with a severe sunlight allergy. As in she couldn't be in direct sunlight for more than about two minutes before her skin would start to burn and blister. She'd already had skin cancer six times by the time she got to high school. She got to leave class early, wear a hat, and run through the halls before passing period, and had a pass to use the elevator instead of the very well-lit staircases. We also had several of the deaf students I'd gone to elementary school with. One of them needed special accommodation in gym class, as she couldn't swim but still had to participate in the swim unit, but she had a permanent aide assigned to her and they did simple kicking exercises in the shallow end where she could stand.
My sister works with an autism program now in an elementary school. She says that they're doing amazing things with those kids, and that they've got such a great response from the district that the program looks like it might be able to expand soon. She's seen so many kids even working half of last year make amazing progress, and she's really looking forward to helping them out again this year.