When I was away at University and doing my own laundry for the first time, I would run out of clothes to wear, hike down the stairs from my 3rd floor dorm room to the basement (four flights, no lift!), cram as much as could fit into the top-loader unsorted, and wash. It's a wonder I didn't have any disasters, but my clothes weren't new so there was no risk of dye leeching, and I lived in tshirts, jeans and hoodies, so nothing requiring special treatment.
Now that I'm more grown-up and have the space, I still wear mostly tshirts, yoga pants, jeans, hoodies, with some nicer stuff as well. I sort my laundry as I remove it after wearing, into piles on the floor.
Load #1: Blacks/grays/browns/reds
Load #2: bright colours (mostly berry pinks, purples, blues, greens)
Load #3: Jeans
Load #4: Towels
Load #5: Bedding
Load #6: Dog blankets/towels
Delicates and hang-dry stuff goes into netted bags for easy identification. I have a larger black one, a white one, and a smaller one that I used to use for baby socks.
Whenever I see enough for a load, I toss one into my H.E. front-load washer. I wash most clothes in cold, towels, bedding and dog stuff in hot, all on a high-speed spin. I had a bar installed over the sink in my tiny laundry room (seriously, there's no room for a hamper in there, just enough to open the front-loading doors of the machines). I use hangers to hang all bras and several tops that are labeled line-dry, as well as many I just don't want to shrink. Some of my clothes have never seen the inside of the dryer, and are in better shape for it. I don't have an outside line (allergic to the outdoors anyway, sub-zero winters, and an HoA that forbids "permanent structures", as well as just no good place to put one, as the city walking trail goes by about 20 feet from the back of my house, and the main-floor deck doesn't have stairs to get down to the backyard anyway). Bedding, towels, dog stuff go into the dryer on low-heat in 25 minute cycles. If it's mostly dry, I remove it and hang over the hallway railing to finish. I hang as much as I can, sometimes giving a quick spin in the dryer to soften jeans. Since I keep the heat low in the winter to avoid atrocious bills, I have been known to toss my fleece blanket into the dryer for 10 minutes to warm it before wrapping up in it
One fun tip: When my father had air conditioning installed in one of our houses, he had a vent put in the bathroom floor under the towel bar, so the towels dried faster, and in the winter the heat would warm the towels, which was quite pleasant.