I do not answer the phone during LOST, period. Not for anyone. I have an answering machine, though, so if someone had an emergency and I heard them yelling "Pick up! PICK UP!" from the other room, I would go answer it, but everyone knows not to call me then. I had the same deal during Star Trek:TNG when it was on too. And I usually don't answer during Desperate Housewives, but people don't call me much on Sunday night.*
The hardest thing has been not answering during school time. I have to cut off people after 8:00 or 8:30 so I can study. Most people understand, but I have one friend who continually calls me after 9. I usually don't answer if I am busy or don't feel like it, and then I call her back the next night.
I WILL answer the door if it's my neighbor, but if it's someone I don't know, I will peek and then ignore it.
*I missed DH last Sunday because of the stupid ice storm...someone tell me please, who is Gabby's secret admirer!!!!!!!!!