Two words: Eat out. Seriously.....I'm terrible at confrontations of any kind, probably because my mom has raised me with the idea that having any kind of boundaries, or not talking to just anyone (when I'd really prefer silence), is "rude." I know now that that's not true, but for a while, it made me a bit of a doormat........I still am, in a way. If you don't have the money or time to eat out every day, then maybe you could bring your iPod or Discman or whatever to work, and when your TMI co-worker starts up, you could always just say you can't hear her over the music......but that this is your favourite song, and you want to hear it. Then start singing or humming along to it, and drown her out even more.....bonus points if you're tone-deaf, lol. But seriously, this way, you won't look like you're being rude, you'll just appear to be distracted.