For me personally, getting little "thanks" messages doesn't bother me at all; I rather like them. But, I'm not inundated with emails/texts/etc. all day either, so it's no hardship for me to check that message. I wouldn't see anything wrong with the conversation with George, for example. In fact it's worse if I put my stuff away (mentally and physically), thinking the issue is closed, only to have to drag it back out later because someone finally realized they had a question or didn't get my earlier message.
I'll tell you one time the social niceties do irritate me, though. If I need customer service-type help, I like to use the chat function if the company has it available (as opposed to phone). I know the employees are working off scripts and are told to be scrupulously polite, but it kind of drives me crazy when every single little thing I do generates a thanks or other generically polite comment. Thank you for giving me that information, thank you for waiting patiently, thank you for breathing... I like to think that they can cut and paste these responses, at least, and aren't wasting time actually typing, "I'm so sorry you're having this issue. I'm going to try my best to help you with that!" It just seems so hollow, you know? I don't want them to be rude, of course, but after a while it's kind of like talking to an excruciatingly polite robot, who may or may not be able to help me. I'd rather have a neutral tone, and get my issue resolved, than get a polite runaround.